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Orthotopic models may provide more clinically relevant insights into the effects of Semaglutide on local invasion, lymphatic dissemination, and distant metastasis of OSCC

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Several GLP-1 RAs, including liraglutide [29], semaglutide [30], and dulaglutide [31], have demonstrated significant efficacy in improving glycemic control and reducing hemoglobin A1C (HbA1c)